A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve

AIMS: The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear. The aim of this study was to mechanistically test short-term late sodium current inhibition...

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Publicado en:Eur Heart J
Main Authors: Bairey Merz, C. Noel, Handberg, Eileen M., Shufelt, Chrisandra L., Mehta, Puja K., Minissian, Margo B., Wei, Janet, Thomson, Louise E.J., Berman, Daniel S., Shaw, Leslee J., Petersen, John W., Brown, Garrett H., Anderson, R. David, Shuster, Jonathan J., Cook-Wiens, Galen, Rogatko, André, Pepine, Carl J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872284/
https://ncbi.nlm.nih.gov/pubmed/26614823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv647
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