A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve

AIMS: The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear. The aim of this study was to mechanistically test short-term late sodium current inhibition...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Bairey Merz, C. Noel, Handberg, Eileen M., Shufelt, Chrisandra L., Mehta, Puja K., Minissian, Margo B., Wei, Janet, Thomson, Louise E.J., Berman, Daniel S., Shaw, Leslee J., Petersen, John W., Brown, Garrett H., Anderson, R. David, Shuster, Jonathan J., Cook-Wiens, Galen, Rogatko, André, Pepine, Carl J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872284/
https://ncbi.nlm.nih.gov/pubmed/26614823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv647
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