Myocardial tissue deformation is reduced in subjects with coronary microvascular dysfunction but not rescued by treatment with ranolazine

BACKGROUND: Patients with coronary microvascular dysfunction (CMD) often have diastolic dysfunction, representing an important therapeutic target. Ranolazine—a late sodium current inhibitor—improves diastolic function in animal models and subjects with obstructive coronary artery disease (CAD). HYPO...

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Detalhes bibliográficos
Publicado no:Clin Cardiol
Main Authors: Nelson, Michael D., Sharif, Behzad, Shaw, Jaime L., Cook‐Wiens, Galen, Wei, Janet, Shufelt, Chrisandra, Mehta, Puja K., Thomson, Louise E. J., Berman, Daniel S., Thompson, Richard B., Handberg, Eileen M., Pepine, Carl J., Li, Debiao, Bairey Merz, C. Noel
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2016
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436931/
https://ncbi.nlm.nih.gov/pubmed/28004395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22660
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