Myocardial tissue deformation is reduced in subjects with coronary microvascular dysfunction but not rescued by treatment with ranolazine

BACKGROUND: Patients with coronary microvascular dysfunction (CMD) often have diastolic dysfunction, representing an important therapeutic target. Ranolazine—a late sodium current inhibitor—improves diastolic function in animal models and subjects with obstructive coronary artery disease (CAD). HYPO...

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Bibliografski detalji
Izdano u:Clin Cardiol
Glavni autori: Nelson, Michael D., Sharif, Behzad, Shaw, Jaime L., Cook‐Wiens, Galen, Wei, Janet, Shufelt, Chrisandra, Mehta, Puja K., Thomson, Louise E. J., Berman, Daniel S., Thompson, Richard B., Handberg, Eileen M., Pepine, Carl J., Li, Debiao, Bairey Merz, C. Noel
Format: Artigo
Jezik:Inglês
Izdano: Wiley Periodicals, Inc. 2016
Teme:
Clinical Investigations
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436931/
https://ncbi.nlm.nih.gov/pubmed/28004395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22660
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