A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve

AIMS: The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear. The aim of this study was to mechanistically test short-term late sodium current inhibition...

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Udgivet i:Eur Heart J
Main Authors: Bairey Merz, C. Noel, Handberg, Eileen M., Shufelt, Chrisandra L., Mehta, Puja K., Minissian, Margo B., Wei, Janet, Thomson, Louise E.J., Berman, Daniel S., Shaw, Leslee J., Petersen, John W., Brown, Garrett H., Anderson, R. David, Shuster, Jonathan J., Cook-Wiens, Galen, Rogatko, André, Pepine, Carl J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Aha Fasttrack
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872284/
https://ncbi.nlm.nih.gov/pubmed/26614823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv647
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