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Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality
Formation of nucleosome free region (NFR) accompanied by specific histone modifications at flanking nucleosomes is an important prerequisite for enhancer and promoter activity. Due to this process, active regulatory elements often exhibit a distinct shape of histone signal in the form of a peak-vall...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872112/ https://ncbi.nlm.nih.gov/pubmed/27095194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw250 |
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