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Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

Formation of nucleosome free region (NFR) accompanied by specific histone modifications at flanking nucleosomes is an important prerequisite for enhancer and promoter activity. Due to this process, active regulatory elements often exhibit a distinct shape of histone signal in the form of a peak-vall...

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Foilsithe in:Nucleic Acids Res
Main Authors: Pundhir, Sachin, Bagger, Frederik O., Lauridsen, Felicia B., Rapin, Nicolas, Porse, Bo T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872112/
https://ncbi.nlm.nih.gov/pubmed/27095194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw250
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