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Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor

OBJECTIVE: To identify target antigens presented by human leukocyte antigen (HLA)–A*02:01 to the myelin-reactive human T-cell receptor (TCR) 2D1, which was originally isolated from a CD8+ T-cell clone recognizing proteolipid protein (PLP) in the context of HLA-A*03:01, we employed a new antigen sear...

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Bibliografiske detaljer
Udgivet i:Neurol Neuroimmunol Neuroinflamm
Main Authors: Rühl, Geraldine, Niedl, Anna G., Patronov, Atanas, Siewert, Katherina, Pinkert, Stefan, Kalemanov, Maria, Friese, Manuel A., Attfield, Kathrine E., Antes, Iris, Hohlfeld, Reinhard, Dornmair, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871805/
https://ncbi.nlm.nih.gov/pubmed/27231714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000241
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