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Peptide binding to HLA-DP proteins at pH 5.0 and pH 7.0: a quantitative molecular docking study
BACKGROUND: HLA-DPs are class II MHC proteins mediating immune responses to many diseases. Peptides bind MHC class II proteins in the acidic environment within endosomes. Acidic pH markedly elevates association rate constants but dissociation rates are almost unchanged in the pH range 5.0 – 7.0. Thi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508589/ https://ncbi.nlm.nih.gov/pubmed/22862845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-12-20 |
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