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Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABA(A) receptors on dendritic spines

Adolescent synaptic pruning is thought to enable optimal cognition because it is disrupted in certain neuropathologies, yet the initiator of this process is unknown. One factor not yet considered is the α4βδ GABA(A) receptor (GABAR), an extrasynaptic inhibitory receptor which first emerges on dendri...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Afroz, Sonia, Parato, Julie, Shen, Hui, Smith, Sheryl Sue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871702/
https://ncbi.nlm.nih.gov/pubmed/27136678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15106
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