The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts

In men, androgens are critical for the acquisition and maintenance of bone mass in both the cortical and cancellous bone compartment. Male mice with targeted deletion of the androgen receptor (AR) in mature osteoblasts or osteocytes have lower cancellous bone mass, but no cortical bone phenotype. We...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Ucer, Serra, Iyer, Srividhya, Bartell, Shoshana M, Martin-Millan, Marta, Han, Li, Kim, Ha-Neui, Weinstein, Robert S, Jilka, Robert L, O’Brien, Charles A, Almeida, Maria, Manolagas, Stavros C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871247/
https://ncbi.nlm.nih.gov/pubmed/25704845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2485
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