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Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual

The detection of estrogen receptor-α (ERα) in osteoblasts and osteoclasts over 20 years ago suggested that direct effects of estrogens on both of these cell types are responsible for their beneficial effects on the skeleton, but the role of ERα in osteoblast lineage cells has remained elusive. In ad...

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Detalhes bibliográficos
Main Authors: Almeida, Maria, Iyer, Srividhya, Martin-Millan, Marta, Bartell, Shoshana M., Han, Li, Ambrogini, Elena, Onal, Melda, Xiong, Jinhu, Weinstein, Robert S., Jilka, Robert L., O’Brien, Charles A., Manolagas, Stavros C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533305/
https://ncbi.nlm.nih.gov/pubmed/23221342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65910
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