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The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone

Estrogens attenuate osteoclastogenesis and stimulate osteoclast apoptosis, but the molecular mechanism and contribution of these effects to the overall antiosteoporotic efficacy of estrogens remain controversial. We selectively deleted the estrogen receptor (ER)α from the monocyte/macrophage cell li...

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Autors principals: Martin-Millan, Marta, Almeida, Maria, Ambrogini, Elena, Han, Li, Zhao, Haibo, Weinstein, Robert S., Jilka, Robert L., O'Brien, Charles A., Manolagas, Stavros C.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817608/
https://ncbi.nlm.nih.gov/pubmed/20053716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0354
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