The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone

Estrogens attenuate osteoclastogenesis and stimulate osteoclast apoptosis, but the molecular mechanism and contribution of these effects to the overall antiosteoporotic efficacy of estrogens remain controversial. We selectively deleted the estrogen receptor (ER)α from the monocyte/macrophage cell li...

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Autores principales: Martin-Millan, Marta, Almeida, Maria, Ambrogini, Elena, Han, Li, Zhao, Haibo, Weinstein, Robert S., Jilka, Robert L., O'Brien, Charles A., Manolagas, Stavros C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817608/
https://ncbi.nlm.nih.gov/pubmed/20053716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0354
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