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Estrogens Attenuate Oxidative Stress and the Differentiation and Apoptosis of Osteoblasts by DNA-Binding-Independent Actions of the ERα

Estrogens diminish oxidative stress in bone and bone marrow, attenuate the generation of osteoblasts, and decrease the prevalence of mature osteoblast apoptosis. We have searched for the molecular mechanism of these effects using as tools a mouse model bearing an estrogen receptor α (ERα) knock-in m...

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Bibliografske podrobnosti
Main Authors: Almeida, Maria, Martin-Millan, Marta, Ambrogini, Elena, Bradsher, Robert, Han, Li, Chen, Xiao-Dong, Roberson, Paula K, Weinstein, Robert S, O'Brien, Charles A, Jilka, Robert L, Manolagas, Stavros C
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153331/
https://ncbi.nlm.nih.gov/pubmed/19821774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091017
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