Continuous Elevation of PTH Increases the Number of Osteoblasts via Both Osteoclast-Dependent and -Independent Mechanisms

Sustained parathyroid hormone (PTH) elevation stimulates bone remodeling (ie, both resorption and formation). The former results from increased RANKL synthesis, but the cause of the latter has not been established. Current hypotheses include release of osteoblastogenic factors from osteoclasts or fr...

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Bibliografiske detaljer
Main Authors: Jilka, Robert L, O'Brien, Charles A, Bartell, Shoshana M, Weinstein, Robert S, Manolagas, Stavros C
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179285/
https://ncbi.nlm.nih.gov/pubmed/20533302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.145
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