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Enzyme kinetics and inhibition of histone acetyltransferase KAT8
Lysine acetyltransferase 8 (KAT8) is a histone acetyltransferase (HAT) responsible for acetylating lysine 16 on histone H4 (H4K16) and plays a role in cell cycle progression as well as acetylation of the tumor suppressor protein p53. Further studies on its biological function and drug discovery init...
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| Pubblicato in: | Eur J Med Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871228/ https://ncbi.nlm.nih.gov/pubmed/26505788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.10.016 |
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