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Intracerebral haemorrhage in Down syndrome: protected or predisposed?

Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with deposition of large amounts of amyloid within the central nervous system. Amyloid accumulates in two compartments: as plaques within the brain parenchyma and in vessel walls of the cerebral microvasculature. The paren...

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Bibliografiska uppgifter
I publikationen:F1000Res
Huvudupphovsmän: Buss, Lewis, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Groet, Jurgen, Pulford, Laura, Strydom, André
Materialtyp: Artigo
Språk:Inglês
Publicerad: F1000Research 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870990/
https://ncbi.nlm.nih.gov/pubmed/27239286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7819.1
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