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Intracerebral haemorrhage in Down syndrome: protected or predisposed?

Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with deposition of large amounts of amyloid within the central nervous system. Amyloid accumulates in two compartments: as plaques within the brain parenchyma and in vessel walls of the cerebral microvasculature. The paren...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Buss, Lewis, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Groet, Jurgen, Pulford, Laura, Strydom, André
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870990/
https://ncbi.nlm.nih.gov/pubmed/27239286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7819.1
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