Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

BACKGROUND: Down syndrome (DS) may be considered a genetic form of Alzheimer’s disease (AD) due to universal development of AD neuropathology, but diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. A potential biomarker is neurofilament light (NF-L), due to its assoc...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Strydom, Andre, Heslegrave, Amanda, Startin, Carla M., Mok, Kin Y., Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891918/
https://ncbi.nlm.nih.gov/pubmed/29631614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0367-x
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