Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy

X-linked adrenoleukodystrophy (X-ALD), the most frequent monogenetic disorder of brain white matter, is highly variable, ranging from slowly progressive adrenomyeloneuropathy (AMN) to life-threatening inflammatory brain demyelination (CALD). In this study involving 94 X-ALD patients and 55 controls,...

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Publicado en:Nat Commun
Main Authors: Weinhofer, Isabelle, Rommer, Paulus, Zierfuss, Bettina, Altmann, Patrick, Foiani, Martha, Heslegrave, Amanda, Zetterberg, Henrik, Gleiss, Andreas, Musolino, Patricia L., Gong, Yi, Forss-Petter, Sonja, Berger, Thomas, Eichler, Florian, Aubourg, Patrick, Köhler, Wolfgang, Berger, Johannes
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985512/
https://ncbi.nlm.nih.gov/pubmed/33753741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22114-2
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