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Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

PURPOSE: As a powerful technology for genome engineering, the CRISPR/Cas system has been successfully applied to modify the genomes of various species. The purpose of this study was to evaluate the technology and establish principles for the introduction of precise genetic modifications in early hum...

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Библиографические подробности
Опубликовано в: :J Assist Reprod Genet
Главные авторы: Kang, Xiangjin, He, Wenyin, Huang, Yuling, Yu, Qian, Chen, Yaoyong, Gao, Xingcheng, Sun, Xiaofang, Fan, Yong
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870449/
https://ncbi.nlm.nih.gov/pubmed/27052831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0710-8
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