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Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

PURPOSE: As a powerful technology for genome engineering, the CRISPR/Cas system has been successfully applied to modify the genomes of various species. The purpose of this study was to evaluate the technology and establish principles for the introduction of precise genetic modifications in early hum...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Kang, Xiangjin, He, Wenyin, Huang, Yuling, Yu, Qian, Chen, Yaoyong, Gao, Xingcheng, Sun, Xiaofang, Fan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870449/
https://ncbi.nlm.nih.gov/pubmed/27052831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0710-8
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