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Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

PURPOSE: As a powerful technology for genome engineering, the CRISPR/Cas system has been successfully applied to modify the genomes of various species. The purpose of this study was to evaluate the technology and establish principles for the introduction of precise genetic modifications in early hum...

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Podrobná bibliografie
Vydáno v:J Assist Reprod Genet
Hlavní autoři: Kang, Xiangjin, He, Wenyin, Huang, Yuling, Yu, Qian, Chen, Yaoyong, Gao, Xingcheng, Sun, Xiaofang, Fan, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870449/
https://ncbi.nlm.nih.gov/pubmed/27052831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0710-8
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