Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia123

Mutations in the superoxide dismutase 1 (SOD1) gene contribute to motoneuron degeneration and are evident in 20% of familial amyotrophic lateral sclerosis cases. Mutant SOD1 induces microglial activation through a stimulation of Toll-like receptors 2 and 4 (TLR2 and TLR4). In the present study, we i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eNeuro
Egile Nagusiak: Kinsella, Sinéad, König, Hans-Georg, Prehn, Jochen H.M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2016
Gaiak:
New Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870272/
https://ncbi.nlm.nih.gov/pubmed/27257617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0099-15.2016
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak