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Chromatin looping as a target for altering erythroid gene expression
The β-hemoglobinopathies are the most common monogenic disorders in humans, with symptoms arising after birth when the fetal γ-globin genes are silenced and the adult β-globin gene is activated. There is a growing appreciation that genome organization and the folding of chromosomes are key determina...
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| 出版年: | Ann N Y Acad Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870130/ https://ncbi.nlm.nih.gov/pubmed/26918894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13012 |
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