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Role of LDB1 in the transition from chromatin looping to transcription activation

Many questions remain about how close association of genes and distant enhancers occurs and how this is linked to transcription activation. In erythroid cells, lim domain binding 1 (LDB1) protein is recruited to the β-globin locus via LMO2 and is required for looping of the β-globin locus control re...

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Detalhes bibliográficos
Main Authors: Krivega, Ivan, Dale, Ryan K., Dean, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066399/
https://ncbi.nlm.nih.gov/pubmed/24874989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.239749.114
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