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LDB1-mediated enhancer looping can be established independent of mediator and cohesin

Mechanistic studies in erythroid cells indicate that LDB1, as part of a GATA1/TAL1/LMO2 complex, brings erythroid-expressed genes into proximity with enhancers for transcription activation. The role of co-activators in establishing this long-range interaction is poorly understood. Here we tested the...

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Publicat a:Nucleic Acids Res
Autors principals: Krivega, Ivan, Dean, Ann
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737898/
https://ncbi.nlm.nih.gov/pubmed/28520978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx433
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