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Carbachol-induced colonic mucus formation requires transport via NKCC1, K(+) channels and CFTR

The colonic mucosa protects itself from the luminal content by secreting mucus that keeps the bacteria at a distance from the epithelium. For this barrier to be effective, the mucus has to be constantly replenished which involves exocytosis and expansion of the secreted mucins. Mechanisms involved i...

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Библиографические подробности
Опубликовано в: :Pflugers Arch
Главные авторы: Gustafsson, Jenny K., Lindén, Sara K., Alwan, Ala H., Scholte, Bob J., Hansson, Gunnar C., Sjövall, Henrik
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869990/
https://ncbi.nlm.nih.gov/pubmed/25139191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1595-y
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