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An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants

The colon mucus layers minimize the contact between the luminal flora and the epithelial cells, and defects in this barrier may lead to colonic inflammation. We now describe an ex vivo method for analysis of mucus properties in human colon and mouse small and large intestine. Intestinal explants wer...

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Autors principals: Gustafsson, Jenny K., Ermund, Anna, Johansson, Malin E. V., Schütte, André, Hansson, Gunnar C., Sjövall, Henrik
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073982/
https://ncbi.nlm.nih.gov/pubmed/22159279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00405.2011
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