Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes

We have reported that transmembrane mucin MUC17 binds PDZ protein PDZK1, which retains MUC17 apically in enterocytes. MUC17 and transmembrane mucins MUC3 and MUC12 are suggested to build the enterocyte apical glycocalyx. Carbachol (CCh) stimulation of the small intestine results in gel-forming mucin...

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Autores principales: Pelaseyed, Thaher, Gustafsson, Jenny K., Gustafsson, Ida J., Ermund, Anna, Hansson, Gunnar C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891215/
https://ncbi.nlm.nih.gov/pubmed/23784542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00141.2013
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