A Single Subunit Directs the Assembly of the Escherichia coli DNA Sliding Clamp Loader

Multi-protein clamp loader complexes are required to load sliding clamps onto DNA. In Escherichia coli the clamp loader contains three DnaX (τ/γ) proteins, δ, and δ′, which together form an asymmetric pentameric ring that also interacts with ψχ. Here we used mass spectrometry to examine the assembly...

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Published in:Structure
Main Authors: Park, Ah Young, Jergic, Slobodan, Politis, Argyris, Ruotolo, Brandon T., Hirshberg, Daniel, Jessop, Linda L., Beck, Jennifer L., Barsky, Daniel, O’Donnell, Mike, Dixon, Nicholas E., Robinson, Carol V.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869865/
https://ncbi.nlm.nih.gov/pubmed/20223211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.01.009
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