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Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis
A diverse 5,000-compound library was synthesized from commercially available diamines and screened for activity against Mycobacterium tuberculosis in vitro, revealing 143 hits with MIC equal to or less than 12.5 µM. New prospective scaffolds with antitubercular activity derived from homopiperazine,...
Gorde:
| Argitaratua izan da: | J Med Chem |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2006
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869334/ https://ncbi.nlm.nih.gov/pubmed/16722620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050948+ |
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