A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma

Background: Evidence suggests that Src homologous protein phosphotyrosyl phosphatase 2 (SHP2) mutations promote cancer development in several solid tumours. In this study, we focused on the in vivo and in vitro effects of an SHP2 mutation on the breast cancer phenotype to determine whether this muta...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hu, Zhongqian, Wang, Xinyi, Fang, Haoshu, Liu, Yakun, Chen, Danlei, Zhang, Qian, Liu, Xia, Wei, Daoyan, Qu, Chengkui, Wang, Siying
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868712/
https://ncbi.nlm.nih.gov/pubmed/26673822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6561
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