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A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma
Background: Evidence suggests that Src homologous protein phosphotyrosyl phosphatase 2 (SHP2) mutations promote cancer development in several solid tumours. In this study, we focused on the in vivo and in vitro effects of an SHP2 mutation on the breast cancer phenotype to determine whether this muta...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868712/ https://ncbi.nlm.nih.gov/pubmed/26673822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6561 |
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