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Integrin alpha-4 is required for regulatory B cell control of experimental autoimmune encephalomyelitis
The neutralization of alpha-4 integrin (Itga4) is currently used as treatment in multiple sclerosis. While most studies focused on its function on lymphocyte migration to the central nervous system, we have uncovered the importance of Itga4 expression on B cells for the generation of regulatory B ce...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868662/ https://ncbi.nlm.nih.gov/pubmed/27016608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502614 |
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