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Integrin alpha-4 is required for regulatory B cell control of experimental autoimmune encephalomyelitis

The neutralization of alpha-4 integrin (Itga4) is currently used as treatment in multiple sclerosis. While most studies focused on its function on lymphocyte migration to the central nervous system, we have uncovered the importance of Itga4 expression on B cells for the generation of regulatory B ce...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Glatigny, Simon, Wagner, Catriona A., Bettelli, Estelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868662/
https://ncbi.nlm.nih.gov/pubmed/27016608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502614
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