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Transient surface CCR5 expression by naïve CD8(+) T cells within inflamed lymph nodes is dependent on HEV interaction and augments helper T-cell dependent memory response()
In inflamed lymph nodes, Ag-specific CD4(+) and CD8(+) T cells encounter Ag-bearing DCs and, together, this complex enhances the release of CCL3 and CCL4 that facilitate additional interaction with naïve CD8(+) T cells. While blocking CCL3 and CCL4 has no effect on primary CD8(+) T cell responses, i...
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| Pubblicato in: | J Immunol |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868656/ https://ncbi.nlm.nih.gov/pubmed/26994221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501176 |
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