CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver

BACKGROUND & AIMS: IL-17 secreting CD4 (Th17) and CD8 (Tc17) T cells have been implicated in immune-mediated liver diseases, but the molecular basis for their recruitment and positioning within the liver is unknown. METHODS: The phenotype and migratory behaviour of human liver-derived Th17 and T...

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Detalhes bibliográficos
Main Authors: Oo, Ye Htun, Banz, Vanessa, Kavanagh, Dean, Liaskou, Evaggelia, Withers, David R., Humphreys, Elizabeth, Reynolds, Gary M., Lee-Turner, Laura, Kalia, Neena, Hubscher, Stefan G., Klenerman, Paul, Eksteen, Bertus, Adams, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994510/
https://ncbi.nlm.nih.gov/pubmed/22796894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2012.07.008
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