Transient surface CCR5 expression by naïve CD8(+) T cells within inflamed lymph nodes is dependent on HEV interaction and augments helper T-cell dependent memory response()

In inflamed lymph nodes, Ag-specific CD4(+) and CD8(+) T cells encounter Ag-bearing DCs and, together, this complex enhances the release of CCL3 and CCL4 that facilitate additional interaction with naïve CD8(+) T cells. While blocking CCL3 and CCL4 has no effect on primary CD8(+) T cell responses, i...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Askew, David, Su, Charles A., Barkauskas, Deborah S., Dorand, R. Dixon, Myers, Jay, Liou, Rachel, Nthale, Joseph, Huang, Alex Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868656/
https://ncbi.nlm.nih.gov/pubmed/26994221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501176
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky