CXCL12 Mediates CCR7-independent Homing of Central Memory Cells, But Not Naive T Cells, in Peripheral Lymph Nodes

Central memory CD8(+) T cells (T(CM)) confer superior protective immunity against infections compared with other T cell subsets. T(CM) recirculate mainly through secondary lymphoid organs, including peripheral lymph nodes (PLNs). Here, we report that T(CM), unlike naive T cells, can home to PLNs in...

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Main Authors: Scimone, M. Lucila, Felbinger, Thomas W., Mazo, Irina B., Stein, Jens V., von Andrian, Ulrich H., Weninger, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211897/
https://ncbi.nlm.nih.gov/pubmed/15096537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031645
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