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The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell–expressed S1P(1) amplifies integrin activation in peripheral lymph nodes but not in Peyer patches
Sphingosine-1-phosphate (S1P) and its receptor S1P(1) control T-cell egress from thymus and secondary lymphoid organs (SLOs). To further define the role of S1P(1) in lymphocyte trafficking, we performed adoptive transfer experiments and intravital microscopy (IVM) using both S1P(1)(–/–) lymphocytes...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society of Hematology
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895188/ https://ncbi.nlm.nih.gov/pubmed/15870184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3687 |
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