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Origin and evolution of developmental enhancers in the mammalian neocortex

Morphological innovations such as the mammalian neocortex may involve the evolution of novel regulatory sequences. However, de novo birth of regulatory elements active during morphogenesis has not been extensively studied in mammals. Here, we use H3K27ac-defined regulatory elements active during hum...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Emera, Deena, Yin, Jun, Reilly, Steven K., Gockley, Jake, Noonan, James P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868431/
https://ncbi.nlm.nih.gov/pubmed/27114548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603718113
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