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Origin and evolution of developmental enhancers in the mammalian neocortex

Morphological innovations such as the mammalian neocortex may involve the evolution of novel regulatory sequences. However, de novo birth of regulatory elements active during morphogenesis has not been extensively studied in mammals. Here, we use H3K27ac-defined regulatory elements active during hum...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Emera, Deena, Yin, Jun, Reilly, Steven K., Gockley, Jake, Noonan, James P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868431/
https://ncbi.nlm.nih.gov/pubmed/27114548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603718113
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