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Origin and evolution of developmental enhancers in the mammalian neocortex

Morphological innovations such as the mammalian neocortex may involve the evolution of novel regulatory sequences. However, de novo birth of regulatory elements active during morphogenesis has not been extensively studied in mammals. Here, we use H3K27ac-defined regulatory elements active during hum...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Emera, Deena, Yin, Jun, Reilly, Steven K., Gockley, Jake, Noonan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868431/
https://ncbi.nlm.nih.gov/pubmed/27114548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603718113
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