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Evolutionary Changes in Promoter and Enhancer Activity During Human Corticogenesis

Human higher cognition is attributed to the evolutionary expansion and elaboration of the human cerebral cortex. However, the genetic mechanisms contributing to these developmental changes are poorly understood. We used comparative epigenetic profiling of human, rhesus macaque and mouse corticogenes...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Reilly, Steven K., Yin, Jun, Ayoub, Albert E., Emera, Deena, Leng, Jing, Cotney, Justin, Sarro, Richard, Rakic, Pasko, Noonan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426903/
https://ncbi.nlm.nih.gov/pubmed/25745175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1260943
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