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The Evolution of Lineage-Specific Regulatory Activities in the Human Embryonic Limb

The evolution of human anatomical features likely involved changes in gene regulation during development. However, the nature and extent of human-specific developmental regulatory functions remain unknown. We obtained a genome-wide view of cis-regulatory evolution in human embryonic tissues by compa...

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Hlavní autoři: Cotney, Justin, Leng, Jing, Yin, Jun, Reilly, Steven K., DeMare, Laura E., Emera, Deena, Ayoub, Albert E., Rakic, Pasko, Noonan, James P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785101/
https://ncbi.nlm.nih.gov/pubmed/23827682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.056
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