Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity

Amylin enhances arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei leptin signaling and synergistically reduces food intake and body weight in selectively bred diet-induced obese (DIO) rats. Since DIO (125)I-amylin dorsomedial nucleus-dorsomedial VMN binding was reduced, we postulated that thi...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Dunn-Meynell, Ambrose A., Le Foll, Christelle, Johnson, Miranda D., Lutz, Thomas A., Hayes, Matthew R., Levin, Barry E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
Neural Control
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868368/
https://ncbi.nlm.nih.gov/pubmed/26676252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00462.2015
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