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Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination

BACKGROUND: We previously reported the case of a 64-year-old man with mediastinitis caused by Staphylococcus aureus in which the infecting bacterium acquired linezolid resistance after only 14 days treatment with linezolid. We therefore investigated relevant clinical isolates for possible mechanisms...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Iguchi, Shigekazu, Mizutani, Tomonori, Hiramatsu, Keiichi, Kikuchi, Ken
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868352/
https://ncbi.nlm.nih.gov/pubmed/27182700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155512
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