Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination

BACKGROUND: We previously reported the case of a 64-year-old man with mediastinitis caused by Staphylococcus aureus in which the infecting bacterium acquired linezolid resistance after only 14 days treatment with linezolid. We therefore investigated relevant clinical isolates for possible mechanisms...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Iguchi, Shigekazu, Mizutani, Tomonori, Hiramatsu, Keiichi, Kikuchi, Ken
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868352/
https://ncbi.nlm.nih.gov/pubmed/27182700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155512
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