Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

Human regulatory T cells (T(reg) cells) that develop from conventional T cells (T(conv) cells) following suboptimal stimulation via the T cell antigen receptor (TCR) (induced T(reg) cells (iT(reg) cells)) express the transcription factor Foxp3, are suppressive, and display an active proliferative an...

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Publicat a:Nat Immunol
Autors principals: De Rosa, Veronica, Galgani, Mario, Porcellini, Antonio, Colamatteo, Alessandra, Santopaolo, Marianna, Zuchegna, Candida, Romano, Antonella, De Simone, Salvatore, Procaccini, Claudio, La Rocca, Claudia, Carrieri, Pietro Biagio, Maniscalco, Giorgia Teresa, Salvetti, Marco, Buscarinu, Maria Chiara, Franzese, Adriana, Mozzillo, Enza, La Cava, Antonio, Matarese, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868085/
https://ncbi.nlm.nih.gov/pubmed/26414764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3269
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