T1D progression is associated with loss of CD3(+)CD56(+) regulatory T cells that control CD8(+) T cell effector functions

An unresolved issue in autoimmunity is the lack of surrogate biomarkers of immunological self-tolerance for disease monitoring. Here, we show that peripheral frequency of a regulatory T cell population, characterized by the co-expression of CD3 and CD56 molecules (T(R3-56)), is reduced in subjects w...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Metab
Hlavní autoři: Terrazzano, Giuseppe, Bruzzaniti, Sara, Rubino, Valentina, Santopaolo, Marianna, Palatucci, Anna Teresa, Giovazzino, Angela, La Rocca, Claudia, de Candia, Paola, Puca, Annibale, Perna, Francesco, Procaccini, Claudio, De Rosa, Veronica, Porcellini, Chiara, De Simone, Salvatore, Fattorusso, Valentina, Porcellini, Antonio, Mozzillo, Enza, Troncone, Riccardo, Franzese, Adriana, Ludvigsson, Johnny, Matarese, Giuseppe, Ruggiero, Giuseppina, Galgani, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272221/
https://ncbi.nlm.nih.gov/pubmed/32500117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-0173-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky