T1D progression is associated with loss of CD3(+)CD56(+) regulatory T cells that control CD8(+) T cell effector functions

An unresolved issue in autoimmunity is the lack of surrogate biomarkers of immunological self-tolerance for disease monitoring. Here, we show that peripheral frequency of a regulatory T cell population, characterized by the co-expression of CD3 and CD56 molecules (T(R3-56)), is reduced in subjects w...

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書誌詳細
出版年:Nat Metab
主要な著者: Terrazzano, Giuseppe, Bruzzaniti, Sara, Rubino, Valentina, Santopaolo, Marianna, Palatucci, Anna Teresa, Giovazzino, Angela, La Rocca, Claudia, de Candia, Paola, Puca, Annibale, Perna, Francesco, Procaccini, Claudio, De Rosa, Veronica, Porcellini, Chiara, De Simone, Salvatore, Fattorusso, Valentina, Porcellini, Antonio, Mozzillo, Enza, Troncone, Riccardo, Franzese, Adriana, Ludvigsson, Johnny, Matarese, Giuseppe, Ruggiero, Giuseppina, Galgani, Mario
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272221/
https://ncbi.nlm.nih.gov/pubmed/32500117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-0173-1
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