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Oscillatory mTOR inhibition and T(reg) increase in kidney transplantation

Intracellular metabolic pathways dependent upon the mammalian target of rapamycin (mTOR) play a key role in immune-tolerance control. In this study, we focused on long-term mTOR-dependent immune-modulating effects in kidney transplant recipients undergoing conversion from calcineurin inhibitors (CNI...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Sabbatini, M, Ruggiero, G, Palatucci, A T, Rubino, V, Federico, S, Giovazzino, A, Apicella, L, Santopaolo, M, Matarese, G, Galgani, M, Terrazzano, G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608513/
https://ncbi.nlm.nih.gov/pubmed/26077103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12669
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